1-(4-硝基苯)-1H-吡啶-2-酮合成路线 （共 9 条）
反应条件
1: With copper(l) iodide in 1,4-dioxane 0.25 h; 2: With potassium phosphate; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane T=110°C; 2 h; Inert atmosphere;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED
Patent: US2009/239848 A1, 2009 ;
Location in patent: Page/Page column 31 ;
US 20090239848 A1
反应条件
copper(l) iodide in N,N-dimethyl-formamide T=110°C; 12 h;
参考文献
Zhang, Huiping; Chen, Bang-Chi; Wang, Bei; Chao, Sam T.; Zhao, Rulin; Lim, Ngiapkie; Balasubramanian, Balu
Synthesis, 2008 , # 10 art. no. M08907SS, p. 1523 - 1526
反应条件
copper(l) iodide; potassium carbonate in N,N-dimethyl-formamide T=150°C; 6 h;
参考文献
Sugahara, Masakatsu; Ukita, Tatsuzo
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 4 p. 719 - 721
反应条件
caesium carbonate in DMF (N,N-dimethyl-formamide) Product distribution / selectivity;
参考文献
WO2004/87646 A2, ;
Page/Page column 106 ;
WO 2004/087646 A2
反应条件
copper(l) iodide; potassium carbonate in N,N-dimethyl-formamide T=150°C; 27 h;
参考文献
Tetrahedron Letters, , vol. 47, # 44 p. 7677 - 7680
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 365,366
参考文献
Croatica Chemica Acta, , vol. 29, p. 127
反应条件
water; ammonium chloride; zinc in tetrahydrofuran; methanol T=20°C;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED
Patent: US2009/239848 A1, 2009 ;
Location in patent: Page/Page column 31 ;
US 20090239848 A1
反应条件
1: 65 percent / HNO3 / 7 h / 130 °C 2: 42 mg / acetone / pyridine / 3 h / 70 °C View Scheme
参考文献
Tohda, Yasuo; Ariga, Masahiro; Kawashima, Toshihide; Matsumura, Eizo
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 1 p. 201 - 204
