4-甲基-2-羟基-6-甲氧基喹啉合成路线 （共 10 条）
反应条件
indium(III) chloride in ethanol T=60°C; P=760.051 Torr; 0.5 h;
参考文献
Rajendran, A.; Karthikeyan, C.; Rajathi, K.; Ragupathy, D.
Journal of Chemical Sciences (Bangalore), 2012 , vol. 124, # 4 p. 877 - 881,5
反应条件
sulfuric acid T=90 - 110°C; 2 h;
参考文献
Liu, Ying; Feng, Yabing; Wang, Renxiao; Gao, Ying; Lai, Luhua
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 13 p. 1639 - 1641
反应条件
1: 73.8 percent / 0.5 h / 140 °C 2: 62.4 percent / H2SO4 / 2 h / 90 - 110 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 13 p. 1639 - 1641
反应条件
1: phosphoryl chloride; phosphorus (V)-chloride 2: aluminium-powder; water; acetic acid View Scheme
参考文献
Rabe et al.
Chemische Berichte, 1931 , vol. 64, p. 2487,2497
反应条件
hydrogen bromide; acetic acid 75 h; Reflux;
参考文献
Priya, Nivedita; Gupta, Anjali; Chand, Karam; Singh, Prabhjot; Kathuria, Abha; Raj, Hanumantharao G.; Parmar, Virinder S.; Sharma, Sunil K.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 11 p. 4085 - 4094
反应条件
trichlorophosphate T=110 - 120°C; 0.5 h;
参考文献
Liu, Ying; Feng, Yabing; Wang, Renxiao; Gao, Ying; Lai, Luhua
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 13 p. 1639 - 1641
反应条件
1: 89.3 percent / POCl3 / 0.5 h / 110 - 120 °C 2: 80.8 percent / KOH / 4 h / 160 °C View Scheme
参考文献
Liu, Ying; Feng, Yabing; Wang, Renxiao; Gao, Ying; Lai, Luhua
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 13 p. 1639 - 1641
反应条件
1: 89.3 percent / POCl3 / 0.5 h / 110 - 120 °C 2: 80.8 percent / KOH / 4 h / 160 °C 3: 20.1 percent / ZnCl2 / 3 h / 160 °C 4: 74.6 percent / OsO4; NaIO4 / 24 h / 24 - 26 °C 5: 95.6 percent / AgNO3; NaOH / 12 h / 20 °C 6: 100 percent / (COCl)2 / 24 h / 20 °C 7: 92 percent / diethyl ether / 3 h / 0 - 15 °C View Scheme
参考文献
Liu, Ying; Feng, Yabing; Wang, Renxiao; Gao, Ying; Lai, Luhua
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 13 p. 1639 - 1641
反应条件
1: 85 percent / KNO3, H2SO4
2: 94 percent / POCl3
3: 82 percent / H2NNH2 / Pd/C / ethanol / Heating
4: 1.) LDA
5: 70 percent / POCl3 / Heating
View Scheme
参考文献
Weber, Robert W.; Cook, James M.
Heterocycles, 1982 , vol. 19, # 11 p. 2089 - 2092
反应条件
1: phosphoryl bromide
2: ethanolic KOH; N2H4+H2O; palladium/CaCO3
View Scheme
参考文献
Nakano
Yakugaku Zasshi, 1959 , vol. 79, p. 310,313
Chem.Abstr., 1959 , p. 16134
