N,N,2,2-四甲基-1,3-丙二胺合成路线 （共 6 条）
反应条件
hydrogen; nickel in methanol
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 24, p. 1241 - 1246
反应条件
methanol; nickel T=70 - 90°C; durch reduktive Aminierung;
参考文献
DE572548 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 1505
参考文献
US2004/102360 A1, ;
US 20040102360 A1
反应条件
4-(N,N-dimethlyamino)pyridine; 1,2-dichloro-ethane in dichloromethane T=20°C; 8 h; Inert atmosphere;
参考文献
Yang, Jee Sun; Song, Doona; Ko, Won Jin; Kim, Bunyea; Kim, Bo-Kyung; Park, Song-Kyu; Won, Misun; Lee, Kiho; Lee, Kyeong; Kim, Hwan Mook; Han, Gyoonhee
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 621 - 628
参考文献
Rohm GmbH
Patent: US4228102 A1, 1980 ;
反应条件
(i) HCO2H, (ii) aq. HCl; Multistep reaction;
参考文献
Hine,J.; Li,W.-S.
Journal of Organic Chemistry, 1975 , vol. 40, # 3 p. 289 - 292
