D-(+)-核糖酸-1,4-内酯合成路线 （共 50 条）
反应条件
hydrogen bromide
1 h; Ambient temperature;
参考文献
Chen, Shin-Yih; Joullie, Madeleine M.
Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2168 - 2174
反应条件
Thermomyces langinosus lipase in acetonitrile
T=35°C; 24 h; Enzymatic reaction; regioselective reaction;
参考文献
Sebrao, Damianni; Sa, Marcus M.; Nascimento, Maria Da Graa
Process Biochemistry, 2011 , vol. 46, # 2 p. 551 - 556
反应条件
Pseudomonas fluorescens lipase AK in acetonitrile
T=35°C; 24 h; Enzymatic reaction; regioselective reaction;
参考文献
Sebrao, Damianni; Sa, Marcus M.; Nascimento, Maria Da Graa
Process Biochemistry, 2011 , vol. 46, # 2 p. 551 - 556
反应条件
Burkholderia cepacia lipase PSL-D in acetonitrile
T=35°C; 24 h; Enzymatic reaction; regioselective reaction;
参考文献
Sebrao, Damianni; Sa, Marcus M.; Nascimento, Maria Da Graa
Process Biochemistry, 2011 , vol. 46, # 2 p. 551 - 556
反应条件
Burkholderia cepacia lipase PSL-C in acetonitrile
T=35°C; 24 h; Enzymatic reaction; regioselective reaction;
参考文献
Sebrao, Damianni; Sa, Marcus M.; Nascimento, Maria Da Graa
Process Biochemistry, 2011 , vol. 46, # 2 p. 551 - 556
反应条件
Candida antarctica lipase B
T=35°C; 6 h; Enzymatic reaction; regioselective reaction;
参考文献
Sebrao, Damianni; Sa, Marcus M.; Nascimento, Maria Da Graa
Process Biochemistry, 2011 , vol. 46, # 2 p. 551 - 556
反应条件
Candida antarctica lipase B
T=35°C; 6 h; Enzymatic reaction; regioselective reaction;
参考文献
Sebrao, Damianni; Sa, Marcus M.; Nascimento, Maria Da Graa
Process Biochemistry, 2011 , vol. 46, # 2 p. 551 - 556
反应条件
1: 92 percent / I2 / 12 h / Ambient temperature
2: 82 percent / imidazole / dimethylformamide / 2.5 h / 60 °C
3: 72 percent / 80percent aq. AcOH / 1.5 h / Heating
4: 96 percent / acetone / 2.5 h / Heating
5: 96 percent / Raney Ni / tetrahydrofuran / 2.5 h / Heating
View Scheme
参考文献
Mann, John; Thomas, Alison
Journal of the Chemical Society, Chemical Communications, 1985 , # 11 p. 737 - 738
反应条件
trifluorormethanesulfonic acid in 1,4-dioxane
pH 3;
参考文献
Jensen, Hanne Stampe; Limberg, Gerrit; Pedersen, Christian
Carbohydrate Research, 1997 , vol. 302, # 1-2 p. 109 - 112
参考文献
Gardner,T.S. et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 503 - 513
