4,6-二氯-2-甲基喹啉合成路线 (共 11 条)
参考文献
Journal of the American Chemical Society, , vol. 79, p. 1670
Journal of the American Chemical Society, , vol. 71, p. 1906,1910
反应条件
trichlorophosphate Vilsmeier-Haack reaction; 17.5 h; Heating;
参考文献
Journal of the Indian Chemical Society, , vol. 81, # 7 p. 598 - 601
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate T=0 - 5°C; 1.5 h; 2: 6-chloro-2-methyl-quinolin-4-ol T=100°C; Vilsmeier-Haack reaction; 17.5 h;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 9 p. 2069 - 2073
反应条件
1: maleic acid; potassium carbonate; palladium / weitere Reagentien Palladium/Kohle und Wasser 2: phosphoryl chloride View Scheme
参考文献
Journal of the American Chemical Society, , vol. 71, p. 1906,1910
反应条件
1: ammonium cerium (IV) nitrate / 40 °C 2: diphenylether / 0.5 h / 250 °C 3: trichlorophosphate / 1.5 h / 80 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 60, # 5 p. 659 - 664
反应条件
1: diphenylether / 0.5 h / |Reflux 2: trichlorophosphate / 3 h / |Reflux View Scheme
参考文献
Medicinal Chemistry Research, , vol. 21, # 10 p. 3073 - 3079,7
反应条件
1.1: diphenyl ether / 240 °C 2.1: phosphorus oxychloride / 1.5 h / 0 - 5 °C 2.2: 5 percent / 17.5 h / 100 °C View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 9 p. 2069 - 2073
反应条件
1: diphenylether / 0.5 h / 250 °C 2: trichlorophosphate / 1.5 h / 80 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 60, # 5 p. 659 - 664
反应条件
1: diphenylether / 0.5 h / 250 °C 2: trichlorophosphate / 1.5 h / 80 °C View Scheme
参考文献
Molecules, , vol. 17, # 5 p. 5870 - 5881
反应条件
hydrazine hydrate Reflux;
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7