3-甲基-4-硝基-1H-吡唑-5-羧酸合成路线 （共 17 条）
反应条件
2: water; NH3 3: ethanol; palladium/charcoal / Hydrogenation 4: 180 - 200 °C View Scheme
参考文献
Robins et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 833,835,836
反应条件
hydrogenchloride in ethanol
参考文献
Massachusetts Institute of Technology
Patent: US4282361 A1, 1981 ;
参考文献
Musante
Gazzetta Chimica Italiana, 1945 , vol. 75, p. 121,133
Full Text Show Details
Robins et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 833,835,836
反应条件
1: SnCl2; water; HCl 2: HCl; water; copper-powder; KBr View Scheme
参考文献
Musante; Mugnaini
Gazzetta Chimica Italiana, 1947 , vol. 77, p. 182,193
反应条件
sulfuric acid, fuming; nitric acid
T=-5 - 60°C; 19 h;
参考文献
Zhang, Da Qiang; Xu, Gao Fei; Fan, Zhi Jin; Wang, Dao Quan; Yang, Xin Ling; Yuan, De Kai
Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 669 - 672
反应条件
1.1: water; sodium hydroxide / methanol / 4 h / Reflux
1.2: pH 2 / Acidic conditions
2.1: sulfuric acid, fuming; nitric acid / 19 h / -5 - 60 °C
View Scheme
参考文献
Zhang, Da Qiang; Xu, Gao Fei; Fan, Zhi Jin; Wang, Dao Quan; Yang, Xin Ling; Yuan, De Kai
Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 669 - 672
反应条件
sulfuric acid; sulfur trioxide; water; nitric acid
参考文献
Musante
Gazzetta Chimica Italiana, 1945 , vol. 75, p. 121,133
反应条件
1: N2H4+H2O
2: durch Nitrierung erhaltenen 3-Methyl-4-nitro-5-<x-nitro-<2>thyenyl>-1(2)H-pyrazols mit KMnO4 in H2O
View Scheme
参考文献
Parrini
Annali di Chimica (Rome, Italy), 1957 , vol. 47, p. 929,949
反应条件
durch Nitrierung erhaltenen 3-Methyl-4-nitro-5-<x-nitro-<2>thyenyl>-1(2)H-pyrazols mit KMnO4 in H2O;
参考文献
Parrini
Annali di Chimica (Rome, Italy), 1957 , vol. 47, p. 929,949
反应条件
2: water; NH3
3: ethanol; palladium/charcoal / Hydrogenation
5: N,N-dimethyl-aniline; POCl3
6: ethanol; NH3 / 150 °C
View Scheme
参考文献
Robins et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 833,835,836
