2-乙酰氨基-6-甲基嘧啶合成路线 （共 34 条）
反应条件
potassium permanganate; sodium hydroxide in water Reflux;
参考文献
Frimannsson, Daniel O.; McCabe, Thomas; Schmitt, Wolfgang; Lawler, Mark; Gunnlaugsson, Thorfinnur
Supramolecular Chemistry, 2010 , vol. 22, # 9 p. 483 - 490
反应条件
1: 16.5 g / KMnO4 / H2O / 3 h / 75 °C 2: HCl / Heating 3: 25 percent / Br2 / CHCl3 View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; BAUMANN, Karlheinz; GOETSCHI, Erwin; GREEN, Luke; JOLIDON, Synese; KNUST, Henner; LIMBERG, Anja; LUEBBERS, Thomas; THOMAS, Andrew
Patent: WO2011/92272 A1, 2011 ;
WO 2011/092272 A1
反应条件
1.1: water; potassium permanganate / 4 h / 75 °C 1.2: pH 4 - 5 2.1: hydrogenchloride / methanol / 18 h / Reflux 3.1: bromine / chloroform / 40 h / 20 °C View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; BAUMANN, Karlheinz; FLOHR, Alexander; GOETSCHI, Erwin; GREEN, Luke; JOLIDON, Synese; KNUST, Henner; LIMBERG, Anja; LUEBBERS, Thomas; THOMAS, Andrew
Patent: WO2011/101304 A2, 2011 ;
WO 2011/101304 A2
参考文献
Adams; Schrecker
Journal of the American Chemical Society, 1949 , vol. 71, p. 1186,1191
