4-(4-氯苯甲酰基)哌啶合成路线 (共 5 条)
反应条件
1: AlCl3 / 1,2-dichloro-ethane / Heating 2: aq. HCl / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 25 p. 5512 - 5532
反应条件
1: SOCl2 / 1 h / 20 °C 2: AlCl3 / 1,2-dichloro-ethane / Heating 3: aq. HCl / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 25 p. 5512 - 5532
反应条件
hydrogenchloride Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 25 p. 5512 - 5532
反应条件
sodium hydrogencarbonate T=20°C;
参考文献
Orjales, Aurelio; Mosquera, Ramon; Toledo, Antonio; Pumar, M. Carmen; Garcia, Neftali; Cortizo, Lourdes; Labeaga, Luis; Innerarity, Ana
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5512 - 5532
反应条件
sodium tetrahydroborate in ethanol
Inert atmosphere;
参考文献
Fuentes, Jose A.; Carpenter, Ian; Kann, Nina; Clarke, Matthew L.
Chemical Communications, 2013 , vol. 49, # 87 p. 10245 - 10247