N-[(三甲基硅基)甲基]苄胺合成路线 （共 25 条）
反应条件
in dimethyl sulfoxide Heating;
参考文献
Sieburth, Scott McN.; Somers, Joseph J.; O'Hare, Heather K.
Tetrahedron, 1996 , vol. 52, # 16 p. 5669 - 5682
参考文献
Canadian Journal of Chemistry, , vol. 55, p. 2589 - 2600
反应条件
in acetonitrile T=65°C; Rate constant;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 12 p. 2411 - 2414
反应条件
in acetonitrile T=65°C; Rate constant;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 12 p. 2411 - 2414
反应条件
in acetonitrile Ambient temperature;
参考文献
Tanaka; Shirai; Sato
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 518 - 520
反应条件
1: 76 percent 2: 85 percent / CSF, / Me3SiOTf, / tetrahydrofuran / 25 h / 60 °C View Scheme
参考文献
Hosomi, Akira; Sakata, Yasuyuki; Sakurai, Hideki
Chemistry Letters, 1984 , p. 1117 - 1120
反应条件
1: in water T=0°C; 2: With potassium carbonate in water T=20°C; 2 h;
参考文献
CELON PHARMA S.A.; MOSZCZYNSKI-PETKOWSKI, Rafal; BOJARSKI, Lukasz; MAJER, Jakub; WIECZOREK, Maciej; DUBIEL, Krzysztof; LAMPARSKA-PRZYBYSZ, Monika
Patent: WO2014/24125 A1, 2014 ;
Location in patent: Page/Page column 24-25 ;
参考文献
Shi, Jin; Stover, James S.; Whitby, Landon R.; Vogt, Peter K.; Boger, Dale L.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 21 p. 6038 - 6041
反应条件
1: formaldehyd; N-benzyl-N-[(trimethylsilyl)methyl]amine T=0°C; 0.166667 h; 2: methanol With potassium carbonate T=20°C; 73 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2006/61711 A1, 2006 ;
Location in patent: Page/Page column 17 ;
反应条件
formaldehyd; potassium carbonate in methanol
参考文献
Bristol-Myers Squibb Pharma Company
Patent: EP934265 B1, 2003 ;
