Fagomine; 桑叶生物碱; (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇合成路线 （共 56 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol; water T=20°C; P=2585.81 Torr;
参考文献
Castillo, Jose A.; Calveras, Jordi; Casas, Josefina; Mitjans, Montserrat; Vinardell, M. Pilar; Parella, Teodor; Inoue, Tomoyuki; Sprenger, Georg A.; Joglar, Jesus; Clapes, Pere
Organic Letters, 2006 , vol. 8, # 26 p. 6067 - 6070
反应条件
1: With lithium aluminium tetrahydride in diethyl ether T=0°C; RefluxInert atmosphere; 2: With KHF2; dihydrogen peroxide in tetrahydrofuran; methanol T=60°C; Fleming-Tamao oxidation; 15 h; Inert atmosphere;
参考文献
Kundu, Pintu K.; Ghosh, Sunil K.
Tetrahedron Asymmetry, 2011 , vol. 22, # 10 p. 1090 - 1096
反应条件
hydrogen; palladium on activated charcoal in methanol; water P=2585.7 Torr; 24 h; Yield given;
参考文献
Heterocycles, , vol. 28, # 1 p. 477 - 480
反应条件
hydrogenchloride; palladium on activated charcoal; hydrogen in ethanol; water 12 h; Inert atmosphere;
参考文献
Min, Im Sook; Kim, Seung In; Hong, Seungmin; Kim, In Su; Jung, Young Hoon
Tetrahedron, 2013 , vol. 69, # 19 p. 3901 - 3906
反应条件
hydrogenchloride; water T=20°C; 24 h;
参考文献
Kim, Ji-Yeon; Mu, Yu; Jin, Xiangdan; Park, Seok-Hwi; Pham, Van-Thoai; Song, Dong-Keun; Lee, Kee-Young; Ham, Won-Hun
Tetrahedron, 2011 , vol. 67, # 48 p. 9426 - 9432
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; P=2585.81 Torr; 24 h;
参考文献
Kumari, Nitee; Reddy, B. Gopal; Vankar, Yashwant D.
European Journal of Organic Chemistry, 2009 , # 1 p. 160 - 169
反应条件
1: With potassium hydroxide in 1,4-dioxane 2: With hydrogenchloride in methanol T=60°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 9 p. 3603 - 3607
反应条件
sulfuric acid in 1,4-dioxane; water
参考文献
Takahata, Hiroki; Banba, Yasunori; Ouchi, Hidekazu; Nemoto, Hideo; Kato, Atsushi; Adachi, Isao
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3603 - 3607
反应条件
hydrogen; palladium hydroxide - carbon in ethanol 12 h;
参考文献
Fleet, George W. J.; Fellows, L. E.; Smith, Paul W.
Tetrahedron, 1987 , vol. 43, # 5 p. 979 - 990
反应条件
hydrogen; palladium on activated charcoal in water; acetic acid P=60004.8 Torr; 0.266667 h; Ambient temperature;
参考文献
Effenberger, Franz; Null, Volker
Liebigs Annalen der Chemie, 1992 , # 11 p. 1211 - 1212
