2-硝基-1,4-苯二胺合成路线 （共 41 条）
反应条件
nickel; hydrazine hydrate in ethanol; 1,2-dichloro-ethane T=50 - 60°C; 6 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 56, # 10 p. 3159 - 3164
反应条件
sulfuric acid; hydrogen; platinum on activated charcoal in acetic acid T=85°C;
参考文献
Lazer, Edward S.; Anderson, James S.; Kijek, James E.; Brown, Keith C.
Synthetic Communications, 1982 , vol. 12, # 9 p. 691 - 694
反应条件
ammonium hydroxide; sodium sulfite in dimethyl sulfoxide T=70°C; 24 h;
参考文献
Forlani, Luciano; Boga, Carla; Mazza, Milena; Cavrini, Vanni; Andrisano, Vincenza
Tetrahedron, 1998 , vol. 54, # 18 p. 4647 - 4654
参考文献
Chemische Berichte, , vol. 40, p. 3179,3183
反应条件
1: acetic acid / 0.25 h / Heating 2: 60percent nitric acid, conc. sulfuric acid / 1.) 0 deg C, 10 min, 2.) RT, 30 min 3: conc. sulfuric acid / 0.25 h / 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 10 p. 1786 - 1792
参考文献
Chemische Berichte, , vol. 44, p. 2927
反应条件
1: 60percent nitric acid, conc. sulfuric acid / 1.) 0 deg C, 10 min, 2.) RT, 30 min 2: conc. sulfuric acid / 0.25 h / 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 10 p. 1786 - 1792
参考文献
Chemische Berichte, , vol. 30, p. 986
Chemische Berichte, , vol. 17, p. 148
反应条件
1: nitric acid / -10 - -5 °C / und verseift das dabei entstandene N-<3-Nitro-4-acetamino-phenyl>-phthalimid durch merhtaegiges Stehenlassen mit Ammoniak oder schneller durch Erhitzen mit Ammoniak 2: KOH-solution View Scheme
参考文献
Chemische Berichte, , vol. 40, p. 3179,3183
反应条件
1: hydrazine hydrate; absolute alcohol 2: hydrazine hydrate 3: acetic acid; water; sodium nitrite 4: alcohol / und verseift das sirupoese Reaktionsprodukt (vielleicht <2-Nitro-4-amino-phenyl>-urethan) mit verd.Natronlauge View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 76, p. 287
