反应条件
1: (1H)-pyrimidine With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; ZnCl2*TMEDA in tetrahydrofuran; hexane
T=0 - 20°C; Inert atmosphere;
2: alpha-chloropyridine With 1,1'-bis-(diphenylphosphino)ferrocene; palladium dichloride in tetrahydrofuran; hexane
24 h; RefluxInert atmosphere;
参考文献
Snegaroff, Katia; Komagawa, Shinsuke; Chevallier, Floris; Gros, Philippe C.; Golhen, Stephane; Roisnel, Thierry; Uchiyama, Masanobu; Mongin, Florence
Chemistry - A European Journal, 2010 , vol. 16, # 27 p. 8191 - 8201