1: 70 percent 2: SO2Cl2 / CH2Cl2 / 1.) 0 deg C, 2.) room temperature View Scheme

1: 3,3'-Dimethoxycarbonylpropanoic anhydride; (hydroxy(tosyloxy)iodo)benzene T=100°C; 0.333333 h; 2: methanol With toluene-4-sulfonic acid 4 h; Heating;

1: With sulfuric acid in methanol; water T=92 - 96°C; 6.5 h; 2: With sodium hydroxide; sodium p-nitrobenzenesulphonic acid in methanol; water T=90 - 94°C; 5.5 h; 3: With sulfuric acid; water in methanol T=35 - 50°C; pH=1.5 - 5.5; 1 h; Product distribution / selectivity;

1: With acetic acid in methanol T=104°C; 6.5 h; 2: With sodium hydroxide; sodium p-nitrobenzenesulphonic acid in methanol; water T=113°C; 5.5 h; 3: With sulfuric acid in methanol; water T=40°C; pH=2.4 - 5.4; 1 h; Product distribution / selectivity;

1: 70 percent 2: 90 percent / Br2 / CCl4 / 1.) -20 deg C, 2.) room temperature View Scheme