1,3,7-三羟基-9H-氧杂蒽-9-酮合成路线 （共 21 条）
反应条件
1: acetone; potassium carbonate 2: Raney nickel / Hydrogenation View Scheme
参考文献
Jain et al.
Journal of Scientific and Industrial Research, 1953 , vol. 12 B, p. 647
反应条件
1: With potassium hydroxide in water T=10°C; 48 h; 2: With hydrogenchloride in water regioselective reaction;
参考文献
Zhang, Xiaojin; Li, Xiang; Tao, Lei; Gao, Yuan; Gong, Dandan; Xi, Meiyang; Xu, Xiaoli; Guo, Qinglong; You, Qidong; Ye, Suofu; Zhang, Yu; Meng, Huyan; Zhang, Mingqian; Gao, Wenlei
Medicinal Chemistry, 2012 , vol. 8, # 6 p. 1012 - 1025,14
反应条件
1: acetone; potassium carbonate 2: sodium acetate View Scheme
参考文献
Rao; Seshadri
Proceedings - Indian Academy of Sciences, Section A, 1953 , # 37 p. 710,715
反应条件
potassium carbonate; acetone
参考文献
Mittal; Seshadri
Journal of Scientific and Industrial Research, 1955 , vol. 14 B, p. 76
反应条件
tin(ll) chloride
T=140°C; 0.0138889 h; Microwave irradiation; regioselective reaction;
参考文献
Verbanac, Donatella; Jain, Subhash C.; Jain, Nidhi; Chand, Mahesh; Cipcic Paljetak, Hana; Matijasic, Mario; Peric, Mihaela; Stepanic, Visnja; Saso, Luciano
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 10 p. 3180 - 3185
反应条件
boron tribromide in dichloromethane
T=-78 - 20°C;
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4992 - 4995
反应条件
1: 100 percent / H2 / Pd/C / methanol / 24 h / 20 °C / 3361.46 Torr
2: 100 percent / KOH / methanol / 12 h / Heating
3: 82 percent / BBr3 / CH2Cl2 / -78 - 20 °C
View Scheme
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4992 - 4995
反应条件
1.1: 98 percent / K2CO3 / acetone / 6 h / Heating
2.1: n-BuLi / tetrahydrofuran / 0.75 h / -78 °C
2.2: 75 percent / tetrahydrofuran / 0.5 h / -78 °C
3.1: 100 percent / H2 / Pd/C / methanol / 24 h / 20 °C / 3361.46 Torr
4.1: 100 percent / KOH / methanol / 12 h / Heating
5.1: 82 percent / BBr3 / CH2Cl2 / -78 - 20 °C
View Scheme
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4992 - 4995
反应条件
1.1: n-BuLi / tetrahydrofuran / 0.75 h / -78 °C
1.2: 75 percent / tetrahydrofuran / 0.5 h / -78 °C
2.1: 100 percent / H2 / Pd/C / methanol / 24 h / 20 °C / 3361.46 Torr
3.1: 100 percent / KOH / methanol / 12 h / Heating
4.1: 82 percent / BBr3 / CH2Cl2 / -78 - 20 °C
View Scheme
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4992 - 4995
反应条件
aluminium trichloride in xylene
1 h; Heating;
参考文献
Mahfouz; Hambloch; Omar; Frahm
Archiv der Pharmazie, 1990 , vol. 323, # 3 p. 163 - 169
