1-(6-甲氧基-2-苯并呋喃基)乙酮合成路线 （共 12 条）
反应条件
nitric acid in acetic anhydride
T=13 - 15°C; 0.75 h;
参考文献
Bachelet, Jean-Pierre; Clavel, Jean-Marc; Demerseman, Pierre; Royer, Rene
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 737 - 739
反应条件
1: zinc / benzene / Heating
2: P2O5 / toluene / 3 h / Heating
3: 47 percent / NBS / CCl4 / 48 h / Heating
4: 58 percent / ammonia (liquid) / tetrahydrofuran / 3 h
5: H2 / Raney nickel / ethanol / 760 Torr / Ambient temperature
View Scheme
参考文献
Berthelot; Vaccher; Flouquet; Luyckx; Brunet; Boulanger; Frippiat; Vercauteren; Debaert; Evrard; Durant
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 395 - 402
反应条件
potassium carbonate
T=100°C; Rapp-Stoermer Benzofuran Synthesis; 0.416667 h; Inert atmosphere;
参考文献
Zhao, Sanhu; Wang, Xiaoju; Zhang, Liwei
Organic Preparations and Procedures International, 2013 , vol. 45, # 5 p. 421 - 428
反应条件
aluminum oxide; 1-ethyl-3-methylimidazolium chloride
0.133333 h; Microwave irradiationIonic liquid;
参考文献
Sapkal, Suryakant B.; Shelke, Kiran F.; Shingate, Bapurao B.; Shingare, Murlidhar S.
Chinese Chemical Letters, 2010 , vol. 21, # 12 p. 1439 - 1442
反应条件
zinc(II) chloride in dichloromethane
T=20°C; 48 h;
参考文献
Del Carmen Cruz, Maria; Tamariz, Joaquin
Tetrahedron, 2005 , vol. 61, # 42 p. 10061 - 10072
反应条件
1: 82 percent / K2CO3 / acetone / 12 h / 60 °C
2: 88 percent / 6 h / 80 °C
3: 62 percent / ZnCl2 / CH2Cl2 / 48 h / 20 °C
View Scheme
参考文献
Del Carmen Cruz, Maria; Tamariz, Joaquin
Tetrahedron, 2005 , vol. 61, # 42 p. 10061 - 10072
反应条件
1: 88 percent / 6 h / 80 °C
2: 62 percent / ZnCl2 / CH2Cl2 / 48 h / 20 °C
View Scheme
参考文献
Del Carmen Cruz, Maria; Tamariz, Joaquin
Tetrahedron, 2005 , vol. 61, # 42 p. 10061 - 10072
反应条件
2: aluminium chloride; carbon disulfide
3: aq. NaOH solution
4: aqueous KOH-solution
View Scheme
参考文献
Gruber; Horvath
Monatshefte fuer Chemie, 1950 , vol. 81, p. 828,834
反应条件
1: aluminium chloride; carbon disulfide
2: aq. NaOH solution
3: aqueous KOH-solution
View Scheme
参考文献
Gruber; Horvath
Monatshefte fuer Chemie, 1950 , vol. 81, p. 828,834
反应条件
1: aq. NaOH solution
2: aqueous KOH-solution
View Scheme
参考文献
Gruber; Horvath
Monatshefte fuer Chemie, 1950 , vol. 81, p. 828,834
