(R)-γ-羟甲基-γ-丁内酯 (R)-4,5-二氢-5-羟甲基-2(3H)-呋喃酮 (R)-5-羟甲基-2-氧代四氢呋喃合成路线 （共 44 条）
反应条件
dimethylsulfide borane complex
参考文献
Harmange, Jean-Christophe; Figadere, Bruno; Hocquemiller, Reynald
Tetrahedron: Asymmetry, 1991 , vol. 2, # 5 p. 347 - 350
反应条件
1: With hydrogenchloride; sodium nitrite in water T=20°C; 70 h; 2: With dimethylsulfide borane complex in tetrahydrofuran T=20°C; 0.16 h;
参考文献
Valot, Gaelle; Regens, Christopher S.; O'Malley, Daniel P.; Godineau, Edouard; Takikawa, Hiroshi; Fuerstner, Alois
Angewandte Chemie - International Edition, 2013 , vol. 52, # 36 p. 9534 - 9538
Angew. Chem., 2013 , vol. 125, # 36 p. 9713 - 9717,5
反应条件
in tetrahydrofuran; methanol
参考文献
Schinazi, Raymond F.; Striker, Robert; Shi, Junxing
Patent: US2004/67877 A1, 2004 ;
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Synthetic Communications, 1990 , vol. 20, # 9 p. 1299 - 1303
反应条件
sodium tetrahydroborate in methanol T=-30 - -15°C; 1 h; Yield given;
参考文献
Bernard, Angela M.; Frongia, Angelo; Piras, Pier P.; Secci, Francesco
Organic Letters, 2003 , vol. 5, # 16 p. 2923 - 2926
反应条件
trifluoroacetic acid T=-10°C; 0.25 h;
参考文献
Ho, Pak-Tsun; Davies, Nancy
Synthesis, 1983 , # 6 p. 462
反应条件
dimethylsulfide borane complex in tetrahydrofuran
参考文献
Figadere; Franck; Cave
Tetrahedron Letters, 1995 , vol. 36, # 10 p. 1637 - 1640
反应条件
PhCH2OLi; hydrogen 1.) THF, 2.) 10percent Pd/C, ether; Yield given. Multistep reaction;
参考文献
Ho, Pak-Tsun; Davies, Nancy
Synthesis, 1983 , # 6 p. 462
反应条件
hydrogenchloride in tetrahydrofuran 0.75 h; Ambient temperature;
参考文献
Teng, Kelly; Marquez, Victor E.; Milne, George W. A.; Barchi Jr., Joseph J.; Kazanietz, Marcelo G.; Lewin, Nancy E.; Blumberg, Peter M.; Abushanab, Elie
Journal of the American Chemical Society, 1992 , vol. 114, # 3 p. 1059 - 1070
反应条件
trifluoroacetic acid T=-10°C; 0.25 h;
参考文献
Liu, Zhi-Yu; Ji, Jian-Xin; Li, Bo-Gang
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3519 - 3521
