3-(三甲基硅基)丙炔醇合成路线 （共 67 条）
反应条件
triethylamine in diethyl ether T=-20 - 20°C;
参考文献
Le Droumaguet, Benjamin; Mantovani, Giuseppe; Haddleton, David M.; Velonia, Kelly
Journal of Materials Chemistry, 2007 , vol. 17, # 19 p. 1916 - 1922
反应条件
manganese(IV) oxide; silica gel T=25°C; 70 h;
参考文献
Mareev, Alexander V.; Medvedeva, Alevtina S.; Khatashkeev, Alexander V.; Afonin, Andrey V.
Mendeleev Communications, 2005 , # 6 p. 263 - 265
反应条件
CuF2 in methanol T=120°C; 0.333333 h; Microwave irradiation;
参考文献
Friscourt, Frederic; Boons, Geert-Jan
Organic Letters, 2010 , vol. 12, # 21 p. 4936 - 4939
反应条件
pyridine; thionyl chloride
参考文献
Jones, Graham B.; Wright, Justin M.; Plourde, Gary W.; Hynd, George; Huber, Robert S.; Mathews, Jude E.
Journal of the American Chemical Society, 2000 , vol. 122, # 9 p. 1937 - 1944
反应条件
1: triethylamine / dichloromethane / 0.67 h / -78 °C / Inert atmosphere
2: sodium azide / N,N-dimethyl-formamide / 0.58 h / 65 °C / Inert atmosphere
3: triphenylphosphine; water / tetrahydrofuran / 2 h / 50 °C
View Scheme
参考文献
Egger, Jonas; Weckerle, Celine; Cutting, Brian; Schwardt, Oliver; Rabbani, Said; Lemme, Katrin; Ernst, Beat
Journal of the American Chemical Society, 2013 , vol. 135, # 26 p. 9820 - 9828
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=0 - 20°C; 2 h;
参考文献
Chakraborty, Tushar K.; Laxman, Pasunoori
Tetrahedron Letters, 2003 , vol. 44, # 27 p. 4989 - 4992
反应条件
1.1: Br2; PPh3 / dimethylformamide / 2 h / 20 °C
2.1: K2CO3 / dimethylformamide / 0.33 h / 20 °C
2.2: 1.59 g / dimethylformamide / 14 h / 20 °C
3.1: 100 percent / TFA / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Anderson; Flaherty; Swarbrick
Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9152 - 9156
反应条件
1H-imidazole; iodine; triphenylphosphine in diethyl ether; acetonitrile
T=0 - 5°C; 0.75 h;
参考文献
Rigby, James H.; Cuisiat, Stephane V.
Journal of Organic Chemistry, 1993 , vol. 58, # 23 p. 6286 - 6291
反应条件
1: 85 percent / LAH / tetrahydrofuran; diethyl ether
2: 78 percent / pyridine / diethyl ether
View Scheme
参考文献
Trost, Barry M.; Self, Christopher R.
Journal of the American Chemical Society, 1983 , vol. 105, # 18 p. 5942 - 5944
反应条件
2-methylpropylmagnesium bromide; bis(cyclopentadienyl)titanium dichloride
1.) Ether, 0 to 25 deg C 2.) Ether, room temp.; Yield given. Multistep reaction;
参考文献
Sato, Fumie; Katsuno, Harutaka
Tetrahedron Letters, 1983 , vol. 24, # 17 p. 1809 - 1810
