3-(三甲基硅基)丙炔醇合成路线 （共 67 条）
反应条件
hydrogenchloride; chloro-(2-methylpropyl)magnesium; bis(cyclopentadienyl)titanium dichloride 1) ether, 25 deg C, 10 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Sato, Fumie; Watanabe, Hiroshi; Tanaka, Youichi; Sato, Masao
Journal of the Chemical Society, Chemical Communications, 1982 , # 19 p. 1126 - 1127
反应条件
trimethylaluminum; diisobutylaluminium hydride 1.) CH2Cl2, 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ma, Shengming; Liu, Fang; Negishi, Ei-Ichi
Tetrahedron Letters, 1997 , vol. 38, # 22 p. 3829 - 3832
反应条件
jones reagent in acetone T=0°C;
参考文献
Nicolaou, K. C.; Li, Wen Sen
Journal of the Chemical Society, Chemical Communications, 1985 , # 7 p. 421
反应条件
o-nitrobenzenesulfonyl hydrazide; triphenylphosphine; diethylazodicarboxylate 1.) THF, -15 deg C, 10 min, 2.) THF, from -15 to 23 deg C; Yield given. Multistep reaction;
参考文献
Myers, Andrew G.; Zheng, Bin
Journal of the American Chemical Society, 1996 , vol. 118, # 18 p. 4492 - 4493
反应条件
pyridine in diethyl ether
参考文献
Ogoshi, Sensuke; Nishiguchi, Shinji; Tsutsumi, Ken; Kurosawa, Hideo
Journal of Organic Chemistry, 1995 , vol. 60, # 14 p. 4650 - 4652
反应条件
1: 30 percent / Br2, triphenylphosphine / dimethylformamide / 18 h / Ambient temperature 2: 70 percent / benzene / 18 h / Ambient temperature View Scheme
参考文献
Corey,E.J. et al.
Tetrahedron Letters, 1973 , p. 3964 - 3966
反应条件
1.1: phosphorus tribromide / -5 - 20 °C / Inert atmosphere 2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -10 °C / Inert atmosphere 2.2: 1 h / -10 °C / Inert atmosphere 3.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -10 °C / Inert atmosphere 3.2: 0 °C / Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 17, # 49 p. 13692 - 13696
反应条件
1: toluene / 4 h / 110 °C 2: 94 percent / DMAP; 1,3-dicyclohexylcarbodiimide / CH2Cl2 / 3 h / 20 °C 3: 97 percent / 4-nitrobenzenesulfonyl azide; Et3N / CH2Cl2 / 12 h / 0 °C View Scheme
参考文献
Padwa, Albert; Straub, Christopher S.
Organic Letters, 2000 , vol. 2, # 14 p. 2093 - 2095
反应条件
hydrogen; nickel in ethanol
参考文献
Komarov,N.V.; Shostakovskii,M.F.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1960 , p. 1208 - 1210
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1960 , # 7 p. 1300 - 1302
反应条件
lithium aluminium tetrahydride in diethyl ether T=0 - 25°C; 6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Denmark, S. E.; Jones, T. K.
Journal of Organic Chemistry, 1982 , vol. 47, # 23 p. 4595 - 4597
