4,6-二氯-2-氨基苯酚合成路线 （共 16 条）
反应条件
hydrogen; platinum(IV) oxide in ethanol T=20°C; P=750.06 Torr; 96 h;
参考文献
Huensch, Sabine; Richter, Wolfgang; Ugi, Ivar; Chattopadhyaya, Jyoti
Liebigs Annalen der Chemie, 1994 , # 3 p. 269 - 276
参考文献
SmithKline Beecham Corporation
Patent: US6262113 B1, 2001 ;
US 6262113 B1
反应条件
in water; sodium hydrogencarbonate
参考文献
Pfizer Inc.
Patent: US4723010 A1, 1988 ;
参考文献
Katz; Cohen
Journal of Organic Chemistry, 1954 , vol. 19, p. 758,762, 765
反应条件
1: fuming nitric acid 2: tin; hydrochloric acid View Scheme
参考文献
Fischer,F.
Justus Liebigs Annalen der Chemie, 1870 , vol. Suppl.7, p. 185
反应条件
1: chlorine 2: fuming nitric acid 3: tin; hydrochloric acid View Scheme
参考文献
Fischer,F.
Justus Liebigs Annalen der Chemie, 1870 , vol. Suppl.7, p. 185
参考文献
Hunter; Barnes
Journal of the Chemical Society, 1928 , p. 2055
反应条件
potassium acetate in ethanol
T=90 - 100°C; 20 h;
参考文献
Agarwal, Nand L.; Schaefer, Wolfram
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2155 - 2161
反应条件
in pyridine
1.) 130 deg C to 140 deg C, 3 h 2.) -2 deg C, 12 h;
参考文献
Agarwal, Nand L.; Schaefer, Wolfram
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5144 - 5149
反应条件
in pyridine
1.) 130 deg C to 140 deg C, 3 h 2.) -2 deg C, 12 h;
参考文献
Agarwal, Nand L.; Schaefer, Wolfram
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5144 - 5149
