(7CI,8CI,9CI)-3-甲基-噻唑并[3,2-a]苯并咪唑合成路线 （共 32 条）
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride
1.) DMSO, reflux, 0.5, 2.) THF, dioxane, 60-80 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Popov, I. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 4 p. 500 - 503
Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 4 p. 567 - 570
反应条件
sodium hydroxide in methanol; water
T=20°C; 1 h;
参考文献
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1167369 A1, 2002 ;
Location in patent: Page 20 ;
EP 1167369 A1
