3-(2-溴-4,5-二甲氧基苯基)丙酸合成路线 （共 10 条）
反应条件
sulfuric acid T=75°C;
参考文献
Haworth; Koepfli; Perkin
Journal of the Chemical Society, 1927 , p. 552
反应条件
dimethylsulfide borane complex in tetrahydrofuran T=0°C; 3 h;
参考文献
Lebel, Helene; Ladjel, Chehla; Brethous, Lise
Journal of the American Chemical Society, 2007 , vol. 129, # 43 p. 13321 - 13326
反应条件
bromine; acetic acid
T=20°C; 3 h;
参考文献
Vincze, Zoltan; Biro, A. Beatrix; Csekei, Marton; Timari, Geza; Kotschy, Andras
Synthesis, 2006 , # 8 p. 1375 - 1385
反应条件
1: NaI / ethanol
2: H2O; ethanol
3: aq. KOH / methanol
4: Br2 / acetic acid
View Scheme
参考文献
Sargent,L.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1754 - 1758
反应条件
1: H2O; ethanol
2: aq. KOH / methanol
3: Br2 / acetic acid
View Scheme
参考文献
Sargent,L.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1754 - 1758
反应条件
1: (i) LiAlH4, Et2O, (ii) aq. H2SO4
2: SOCl2, PhNMe2 / CHCl3
3: NaI / ethanol
4: H2O; ethanol
5: aq. KOH / methanol
6: Br2 / acetic acid
View Scheme
参考文献
Sargent,L.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1754 - 1758
反应条件
1: aq. KOH / methanol
2: Br2 / acetic acid
View Scheme
参考文献
Sargent,L.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1754 - 1758
反应条件
1: SOCl2, PhNMe2 / CHCl3
2: NaI / ethanol
3: H2O; ethanol
4: aq. KOH / methanol
5: Br2 / acetic acid
View Scheme
参考文献
Sargent,L.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1754 - 1758
反应条件
1: acetic acid; bromine
2: methanol
View Scheme
参考文献
Whaley; Robinson
Journal of Organic Chemistry, 1954 , vol. 19, p. 1029,1031
参考文献
Whaley; Robinson
Journal of Organic Chemistry, 1954 , vol. 19, p. 1029,1031
