2,3-二甲氧基氢化喹啉合成路线 (共 10 条)
参考文献
Paquette, Leo A.; Bellamy, Francois; Wells, Gregory J.; Boehm, Michael C.; Gleiter, Rolf
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7122 - 7133
参考文献
Baker; Smith
Journal of the Chemical Society, 1931 , p. 2542,2546
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Nagy, Zoltan; Nogradi, Mihaly; Suranyi, Mihaly; Szabo, Bela
Liebigs Annalen der Chemie, 1984 , # 1 p. 127 - 132
反应条件
1: 36 percent / K2CO3 / dimethylformamide
2: 85 percent / phosphorylchloride / 4 h / 60 °C
View Scheme
参考文献
Nagy, Zoltan; Nogradi, Mihaly; Suranyi, Mihaly; Szabo, Bela
Liebigs Annalen der Chemie, 1984 , # 1 p. 127 - 132
反应条件
anhydrous sulfurous acid
参考文献
Weygand et al.
Chemische Berichte, 1957 , vol. 90, p. 1879,1890
反应条件
sodium hydroxide; dipotassium peroxodisulfate
参考文献
Baker; Savage
Journal of the Chemical Society, 1938 , p. 1602,1605
参考文献
Astrazeneca AB
Patent: US6472435 B1, 2002 ;
US 6472435 B1
参考文献
Baker; Savage
Journal of the Chemical Society, 1938 , p. 1602,1605
反应条件
1: aqueous methanol. NaOH-solution
2: aq. NaOH solution; aqueous potassium peroxo disulfate
3: 200 °C
View Scheme
参考文献
Baker; Savage
Journal of the Chemical Society, 1938 , p. 1602,1605
反应条件
1: aq. NaOH solution; aqueous potassium peroxo disulfate
2: 200 °C
View Scheme
参考文献
Baker; Savage
Journal of the Chemical Society, 1938 , p. 1602,1605