4-(4-吡啶基)-1-丁醇合成路线 （共 13 条）
反应条件
10 Pd/C; hydrogen in ethanol T=20°C; P=760.051 Torr; 6 h;
参考文献
Capuano, Ben; Crosby, Ian T.; Lloyd, Edward J.; Podloucka, Anna; Taylor, David A.
Australian Journal of Chemistry, 2008 , vol. 61, # 12 p. 930 - 940
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol; hexane
参考文献
Merck and Co., Inc.
Patent: US5312923 A1, 1994 ;
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Mayer, Joachim M.; Testa, Bernard
Helvetica Chimica Acta, 1982 , vol. 65, # 6 p. 1868 - 1884
参考文献
Merck and Co., Inc.
Patent: US5780437 A1, 1998 ;
US 5780437 A
反应条件
1: Pd(PPh3)4; LiCl; CuCl / 80 °C 2: H2 / PtO2 / ethanol / 20 °C View Scheme
参考文献
Lin, Peter; Parikh, Mamta; Lo, Jane-Ling; Yang, Yi Tien; Cheng, Kang; Smith, Roy G; Fisher, Michael H; Wyvratt, Matthew J; Goulet, Mark T
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 8 p. 1077 - 1080
参考文献
Dainippon Pharmaceutical Company, Limited
Patent: US6555557 B1, 2003 ;
反应条件
1: 83 percent 2: 87 percent / LiAlH4 / diethyl ether View Scheme
参考文献
Mayer, Joachim M.; Testa, Bernard
Helvetica Chimica Acta, 1982 , vol. 65, # 6 p. 1868 - 1884
反应条件
1: 72 percent / dimethylsulfoxide 2: 83 percent 3: 87 percent / LiAlH4 / diethyl ether View Scheme
参考文献
Mayer, Joachim M.; Testa, Bernard
Helvetica Chimica Acta, 1982 , vol. 65, # 6 p. 1868 - 1884
反应条件
hydrogenchloride 12 h;
参考文献
Desaubry, Laurent; Riche, Stephanie; Laeuffer, Patricia; Cazenave, Jean-Pierre
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 6 p. 2028 - 2031
反应条件
hydrogen; acetic acid; platinum(IV) oxide P=3102.97 Torr; 96 h;
参考文献
Desaubry, Laurent; Riche, Stephanie; Laeuffer, Patricia; Cazenave, Jean-Pierre
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 6 p. 2028 - 2031
