benzotriazol-1-ol; dicyclohexyl-carbodiimide in tetrahydrofuran T=0 - 20°C; pH=9; 8 h;

4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide in dichloromethane T=0 - 20°C;

1: methanesulfonic acid / acetonitrile / 1 h / 25 °C 2: iPr2NEt; 1-hydroxybenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide / acetonitrile; dimethylformamide / 16 h View Scheme

benzotriazol-1-ol; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide; acetonitrile 16 h;