hydrogen; palladium 10 on activated carbon in ethanol
sealed flask;
参考文献
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY; FLORIDA INSTITUTE OF TECHNOLOGY; POWELL, William S.; ROKACH, Joshua
Patent: WO2010/127452 A1, 2010 ;
Location in patent: Page/Page column 52 ;
1: indole With lithium hydride in tetrahydrofuran
Metallation; 24 h; Heating;
2: 1-iodo-n-hexane in tetrahydrofuran
Substitution; alkylation; 24 h; Heating; Further stages.;
参考文献
Abel, Ernesto; De Wall, Stephen L.; Edwards, W. Barry; Lalitha; Covey, Douglas F.; Gokel, George W.
Journal of Organic Chemistry, 2000 , vol. 65, # 19 p. 5901 - 5909