7,16-二[(4-甲基苯基)磺酰基]-1,4,10,13-四氧杂-7,16-二氮杂环十八烷合成路线 （共 18 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 20 h; Heating;
参考文献
Luk'yanenko, N.G.; Basok, S.S.; Filonova, L.K.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 8 p. 1731 - 1742
反应条件
in N,N-dimethyl-formamide Ambient temperaturemercury-cathode, platinum-anode;
参考文献
Engels, Rainer; Smit, Cornelis J.; Tilborg, Wim J. M. van
Angewandte Chemie, 1983 , vol. 95, # 6 p. 502 - 503
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide in toluene
10 h; Heating;
参考文献
Bogatsky, A. V.; Lukyanenko, N. G.; Basok, S. S.; Ostrovskaya, L. K.
Synthesis, 1984 , # 2 p. 138
反应条件
tetrabutyl-ammonium chloride; potassium carbonate in N,N-dimethyl-formamide
T=80°C; 12 h;
参考文献
Ostaszewski, Ryszard; Jacobsson, Ulla; Jurczak, Janusz
Bulletin of the Polish Academy of Sciences, Chemistry, 1988 , vol. 36, # 5-6 p. 221 - 228
反应条件
tetrabutyl-ammonium chloride; potassium carbonate in N,N-dimethyl-formamide
T=80°C; 12 h;
参考文献
Ostaszewski, Ryszard; Jacobsson, Ulla; Jurczak, Janusz
Bulletin of the Polish Academy of Sciences, Chemistry, 1988 , vol. 36, # 5-6 p. 221 - 228
反应条件
in N,N-dimethyl-formamide
T=80°C; 5 h;
参考文献
Bottino, Francesco; Grazia, Michele Di; Finocchiaro, Paolo; Fronczek, Frank R.; Mamo, Antonino; Pappalardo, Sebastiano
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3521 - 3529
反应条件
1: 96 percent / sodium carbonate / H2O / 4 h / Heating
2: 79 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H2O / 9 h / Heating
View Scheme
参考文献
Luk'yanenko, N.G.; Basok, S.S.; Filonova, L.K.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 8 p. 1731 - 1742
反应条件
1: 96 percent / sodium carbonate / H2O / 4 h / Heating
2: 79 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H2O / 9 h / Heating
View Scheme
参考文献
Luk'yanenko, N.G.; Basok, S.S.; Filonova, L.K.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 8 p. 1731 - 1742
反应条件
1: 75 percent / triethylamine / CH2Cl2 / 48 h / 5 °C
2: 1.) NaH / 1.) THF, mineral oil, reflux, 2 h, 2.) THF, reflux, 48 h
View Scheme
参考文献
Vries, Erik F. J. de; Steenwinkel, Pablo; Brussee, Johannes; Kruse, Chris G.; Gen, Arne van der
Journal of Organic Chemistry, 1993 , vol. 58, # 16 p. 4315 - 4325
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide in toluene
Heating;
参考文献
Lukyanenko, Nikolai G.; Basok, Stepan S.; Filonova, Lyubov K.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 3141 - 3148
