3-甲基-1H-吲哚-2-甲醛合成路线 （共 33 条）
反应条件
1: sodium amalgam; disodium hydrogenphosphate / methanol / 1 h / 20 °C / |Inert atmosphere 2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / 1 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Dethe, Dattatraya H.; Erande, Rohan D.; Ranjan, Alok
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10106 - 10120
参考文献
Wilson, R. Marshall; Hengge, Alvan
Tetrahedron Letters, 1985 , vol. 26, # 31 p. 3673 - 3676
参考文献
Katritzky, Alan R.; Akutagawa, Kunihiko; Jones, R Alan
Synthetic Communications, 1988 , vol. 18, # 10 p. 1151 - 1158
反应条件
1: lithium alanate; diethyl ether 2: potassium permanganate; acetone View Scheme
参考文献
Taylor
Helvetica Chimica Acta, 1950 , vol. 33, p. 164,167
Helvetica Chimica Acta, 1954 , vol. 34, p. 787
反应条件
oxygen 7 h; Heating;
参考文献
Itahara, Toshio; Ouya, Hiroshi; Kozono, Kiyotake
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 12 p. 3861 - 3864
反应条件
sodium hydroxide; water; trichlorophosphate 1.) 1,2-dichloroethane, reflux, 15 min, 2.) 5 min; Yield given. Multistep reaction;
参考文献
Bailey, A. Sydney; Scott, Peter W.; Vandrevala, Marazban H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 97 - 101
反应条件
sulfuric acid; peroxomonosulfate(1-) in methanol; water KineticsMechanismRate constant;
参考文献
Balon; Munoz; Guardado; Hidalgo; Carmona
Journal of Organic Chemistry, 1993 , vol. 58, # 26 p. 7469 - 7473
反应条件
Vilsmeier-Haack formylation;
参考文献
Kashimura, Masato; Kikugawa, Yasuo
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2892 - 2894
反应条件
sulfuric acid; peroxomonosulfate(1-) in methanol; water KineticsMechanismRate constant;
参考文献
Balon; Munoz; Guardado; Hidalgo; Carmona
Journal of Organic Chemistry, 1993 , vol. 58, # 26 p. 7469 - 7473
反应条件
in diethyl ether; dichloromethane 1) -70 deg C 2) 1.5h, -15 deg C;
参考文献
Pindur; Flo
Archiv der Pharmazie, 1990 , vol. 323, # 2 p. 79 - 81
