6-氯-2,3-二氢-1H-吲哚合成路线 (共 5 条)
反应条件
sodium cyanoborohydride; acetic acid T=20°C; 0.333333 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2003/76398 A2, 2003 ;
Location in patent: Page/Page column 41 ;
WO 03/076398 A2
反应条件
T=650°C; Product distribution;
参考文献
Abramovitch, Rudolph A.; Holcomb, William D.; Wake, Shigeo
Journal of the American Chemical Society, 1981 , vol. 103, # 6 p. 1525 - 1533
反应条件
T=650°C; 0.26 h; Product distribution;
参考文献
Abramovitch, Rudolph A.; Holcomb, William D.; Wake, Shigeo
Journal of the American Chemical Society, 1981 , vol. 103, # 6 p. 1525 - 1533
反应条件
sodium cyanoborohydride in acetic acid 10 h;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: WO2004/18414 A2, 2004 ;
Location in patent: Page 135-136 ;
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in toluene 6 h; Heating; Rate constantMechanism;
参考文献
Journal of Organic Chemistry, , vol. 55, # 2 p. 580 - 584