3-(三氟甲基)苯乙胺合成路线

Groutas, W. C.; Brubaker, M. J.; Zandler, M. E.; Mazo-Gray, V.; Rude, S. A.; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 7 p. 1302 - 1305

75-52-5硝基甲烷+

454-89-73-三氟甲基苯甲醛

→

52516-30-03-(三氟甲基)苯乙胺

参考文献

Setola, Vincent; Dukat, Malgorzata; Glennon, Richard A.; Roth, Bryan L.
Molecular Pharmacology, 2005 , vol. 68, # 1 p. 20 - 33

402-24-4间三氟甲基苯乙烯

→

59382-36-41-(3-三氟甲基苯基)乙胺+

52516-30-03-(三氟甲基)苯乙胺

参考文献

Ramachandran, P. Veeraraghavan; Madhi, Sateesh; O'Donnell, Martin J.
Journal of Fluorine Chemistry, 2006 , vol. 127, # 9 p. 1252 - 1255

52516-30-03-(三氟甲基)苯乙胺

→

1365760-11-7

参考文献

NOVARTIS AG; Bock, Mark Gary; Gaul, Christoph; Gummadi, Venkateshwar Rao; Moebitz, Henrik; Sengupta, Saumitra
Patent: US2014/45872 A1, 2014 ;