1-甲基-4,9-二氢-3H-吡啶并[3,4-b]吲哚合成路线 （共 19 条）
反应条件
1: 94 percent / Et3N / CH2Cl2 / 0 °C 2: 87 percent / acetonitrile; CH2Cl2 / 20 °C / Electrochemical reaction 3: 60 percent / Na; naphthalene / 1,2-dimethoxy-ethane / 0 °C 4: 74 percent / MnO2 / CH2Cl2 / 20 °C 5: HCl 6: 50 percent / Cu / pyridine View Scheme
参考文献
Roessler, Ulrich; Blechert, Siegfried; Steckhan, Eberhard
Tetrahedron Letters, 1999 , vol. 40, # 39 p. 7075 - 7078
反应条件
potassium permanganate in acetone T=20°C;
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela
Heterocycles, 2005 , vol. 65, # 10 p. 2483 - 2492
反应条件
1: benzene / 1 h / Heating
2: 1.15 g / benzene / 20 h / Irradiation
View Scheme
参考文献
Giri, Venkatachalam S.; Maiti, Bhim C.; Pakrashi, Satyesh C.
Heterocycles, 1984 , vol. 22, # 2 p. 233 - 236
反应条件
in methanol
24 h; Ambient temperature;
参考文献
Giri, Venkatachalam S.; Maiti, Bhim C.; Pakrashi, Satyesh C.
Heterocycles, 1984 , vol. 22, # 2 p. 233 - 236
反应条件
in dichloromethane
T=23°C; overnight;
参考文献
Bobowski
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 473 - 479
反应条件
1: 94 percent / Et3N / CH2Cl2 / 0 °C
2: 87 percent / acetonitrile; CH2Cl2 / 20 °C / Electrochemical reaction
3: 60 percent / Na; naphthalene / 1,2-dimethoxy-ethane / 0 °C
4: 74 percent / MnO2 / CH2Cl2 / 20 °C
View Scheme
参考文献
Roessler, Ulrich; Blechert, Siegfried; Steckhan, Eberhard
Tetrahedron Letters, 1999 , vol. 40, # 39 p. 7075 - 7078
反应条件
trichlorophosphate in toluene; acetonitrile
4 h; Reflux;
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
hydrogenchloride; sodium nitrite in ethanol
T=37°C; pH=3; 1 h;
参考文献
Diem, Stefanie; Gutsche, Birgit; Herderich, Markus
Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 12 p. 5993 - 5998
反应条件
in methanol; water
T=25°C; 6 h; +0.8V/32mA; anode: graphite felt, cathode: Pt, electrolyte: KH2PO4/K2HPO4;
参考文献
Bobbitt, James M.; Willis, John P.
Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1978 - 1984
反应条件
PPA in dichloromethane
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela
Heterocycles, 2005 , vol. 65, # 10 p. 2483 - 2492
