2-丁基-3-(4-羟基苯甲酰基)苯并呋喃合成路线 （共 7 条）
反应条件
aluminium chloride in anhydrous dichloroethane; water
参考文献
Sanofi
Patent: US5266711 A1, 1993 ;
反应条件
sodium hydrogencarbonate; aluminium chloride in water; methoxybenzene
参考文献
Sanofi
Patent: US5266711 A1, 1993 ;
反应条件
1.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice 1.2: 75 h / 0 - 20 °C 2.1: ethyl mercaptan sodium salt / N,N-dimethyl-formamide / 16 h / 110 °C View Scheme
参考文献
J-PHARMA CO., LTD.; WEMPE, Michael, F.; ENDOU, Hitoshi
Patent: WO2012/48058 A2, 2012 ;
WO 2012/048058 A2
反应条件
1.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice 1.2: 75 h / 0 - 20 °C 2.1: ethyl mercaptan sodium salt / N,N-dimethyl-formamide / 16 h / 110 °C View Scheme
参考文献
J-PHARMA CO., LTD.; WEMPE, Michael, F.; ENDOU, Hitoshi
Patent: WO2012/48058 A2, 2012 ;
WO 2012/048058 A2
反应条件
in methanol; water; acetic acid; N,N-dimethyl-formamide
反应条件
iodine; iodic acid in acetic acid
参考文献
Ha; Stieger; Grassi; Altorfer; Follath
European Journal of Clinical Pharmacology, 2000 , vol. 55, # 11-12 p. 807 - 814
反应条件
potassium hydroxide; sodium hypochlorite; sodium iodide in methanol T=-5°C; 4 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 22 p. 5920 - 5922
