3’-氨基-2’,3’-双脱氧胸苷合成路线 （共 24 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Threlfall, Richard; Davies, Andrew; Howarth, Nicola; Cosstick, Richard
Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 6-7 p. 611 - 614
反应条件
silica gel; trifluoroacetic acid in methanol; chloroform
参考文献
Pathak, Ashish K.; Pathak, Vibha; Seitz, Lainne E.; Tiwari, Kamal N.; Akhtar, Mohammad S.; Reynolds, Robert C
Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7755 - 7757
反应条件
methylamine in ethanol 2.5 h; Heating;
参考文献
Motawia; Wengel; Abdel-Megid; Pedersen
Synthesis, 1989 , # 5 p. 384 - 387
反应条件
ammonia in pyridine; water 0.666667 h;
参考文献
Cano-Soldado, Pedro; Molina-Arcas, Miriam; Alguero, Berta; Larrayoz, Ignacio; Lostao, M. Pilar; Grandas, Anna; Casado, F.Javier; Pastor-Anglada, Marcal
Biochemical Pharmacology, 2008 , vol. 75, # 3 p. 639 - 648
反应条件
hydrogen; acetic acid; palladium on activated charcoal Yield given. Multistep reaction;
参考文献
Karl; Lemmen; Ugi
Synthesis, 1989 , # 9 p. 718 - 719
反应条件
1: Dowex 50 x 2 (H+) / methanol / Ambient temperature 2: H2 / 10percent Pd/C / methanol / 36 h / 760 Torr View Scheme
参考文献
Maillard, Michel; Faraj, Abdesslem; Frappier, Francois; Florent, Jean-Claude; Grierson, David S.; Monneret, Claude
Tetrahedron Letters, 1989 , vol. 30, # 15 p. 1955 - 1958
反应条件
1: 41 percent / NaN3 / dimethylformamide / 24 h / Heating 2: 1) 80percent AcOH 2) H2 / 2) 10percent Pd/C View Scheme
参考文献
Matsuda, Akira; Watanabe, Kyoichi A.; Fox, Jack J.
Journal of Organic Chemistry, 1980 , vol. 45, # 16 p. 3274 - 3278
反应条件
1: 39 percent / CF3SO2-OSiMe3 / acetonitrile / 2 h / -30 °C 2: 89 percent / 33percent MeNH2 / ethanol / 2.5 h / Heating View Scheme
参考文献
Motawia; Wengel; Abdel-Megid; Pedersen
Synthesis, 1989 , # 5 p. 384 - 387
反应条件
1: 39 percent / CF3SO2-OSiMe3 / acetonitrile / 2 h / -30 °C 2: 89 percent / 33percent MeNH2 / ethanol / 2.5 h / Heating View Scheme
参考文献
Motawia; Wengel; Abdel-Megid; Pedersen
Synthesis, 1989 , # 5 p. 384 - 387
反应条件
1: 85 percent / NaN3 / dimethylformamide / 120 °C 2: Dowex 50(H+) / methanol 3: H2 / Pd/C / methanol View Scheme
参考文献
Maillard, Michel; Faraj, Abdesslem; Frappier, Francois; Florent, Jean-Claude; Grierson, David S.; Monneret, Claude
Tetrahedron Letters, 1989 , vol. 30, # 15 p. 1955 - 1958
