反应条件
1: 81 percent / nickel(II) chloride / tetrahydrothiophene 1,1-dioxide / 23 h / Heating
2: 74.4 percent / lithium diethylamide / diethyl ether / 3 h / Heating
3: 1.) NH3 (liq.), Na, 2.) hydrogen peroxide / 1) -50 deg C, 1.5 h; 2) THF, H2O, 45 deg C, 1.75 h, room temperature (overnight)
View Scheme
参考文献
Cornforth, John; Cornforth, R. H.; Gray, Robin T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2289 - 2298