1-苄基吡咯烷-2,5-二羧酸二乙酯合成路线 （共 4 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-78 - 20°C; 5 h;
参考文献
JANSSEN PHARMACEUTICA, N.V.
Patent: WO2007/81995 A2, 2007 ;
Location in patent: Page/Page column 190 ;
WO 2007/081995 A2
反应条件
1: xylene / Heating 2: 230 °C 3: H2; HCl / Pd/C / H2O / 85 h / 760 Torr 4: LiAlH4 / diethyl ether / Heating View Scheme
参考文献
Smith, Stephen C; Bentley, Philip D
Tetrahedron Letters, 2002 , vol. 43, # 5 p. 899 - 902
反应条件
1: xylene / Heating 2: 230 °C 3: H2; HCl / Pd/C / H2O / 85 h / 760 Torr 4: LiAlH4 / diethyl ether / Heating 5: CH2Cl2 / 20 °C View Scheme
参考文献
Smith, Stephen C; Bentley, Philip D
Tetrahedron Letters, 2002 , vol. 43, # 5 p. 899 - 902
反应条件
1: xylene / Heating 2: 230 °C 3: H2; HCl / Pd/C / H2O / 85 h / 760 Torr 4: LiAlH4 / diethyl ether / Heating 5: CH2Cl2 / 20 °C 6: 72 percent / H2 / Pd/C / methanol / 760 Torr View Scheme
参考文献
Smith, Stephen C; Bentley, Philip D
Tetrahedron Letters, 2002 , vol. 43, # 5 p. 899 - 902
