2'-脱氧-5-羟基-胞苷合成路线 （共 7 条）
反应条件
1: With bromine in water Bromination; 2: With 2,3,5-trimethyl-pyridine; water Hydrolysis;
参考文献
LaFrancois, Christopher J.; Fujimoto, June; Sowers, Lawrence C.
Chemical Research in Toxicology, 1998 , vol. 11, # 1 p. 75 - 83
反应条件
water; N-ethyl-N,N-diisopropylamine Yield given;
参考文献
Suzuki, Toshinori; Ida, Kazuya; Uchibe, Shinya; Inukai, Michiyo
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 9 p. 5164 - 5170
反应条件
2-methyl-1,4-naphthalenedione; water; oxygen T=10°C; Irradiation; Further byproducts given;
参考文献
Wagner, J. Richard; Decarroz, Chantal; Berger, Maurice; Cadet, Jean
Journal of the American Chemical Society, 1999 , vol. 121, # 17 p. 4101 - 4110
反应条件
tetrabutylammonium fluoride; peroxynitrite in phosphate buffer T=37°C; pH=7.4; 5 h;
参考文献
Suzuki, Toshinori; Ida, Kazuya; Uchibe, Shinya; Inukai, Michiyo
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 9 p. 5164 - 5170
反应条件
1: Br2 / H2O / Ambient temperature 2: H2O, N,N-diisopropylethylamine View Scheme
参考文献
Wang, Jianying; Lin, Kuei-Ying; Matteucci, Mark D.
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8385 - 8388
反应条件
2-methyl-1,4-naphthalenedione; water; oxygen T=10°C; Irradiation; Mechanism;
参考文献
Wagner, J. Richard; Decarroz, Chantal; Berger, Maurice; Cadet, Jean
Journal of the American Chemical Society, 1999 , vol. 121, # 17 p. 4101 - 4110
反应条件
pyridine; formic acid in water T=37°C; Hydrolysis; Kinetics; Further Variations:ReagentsTemperatures;
参考文献
Douki, Thierry; Delatour, Thierry; Paganon, Frederique; Cadet, Jean
Chemical Research in Toxicology, 1996 , vol. 9, # 7 p. 1145 - 1151
