2-氯-N-吡啶-2-基乙酰胺合成路线 （共 8 条）
反应条件
1: in 1,2-dichloro-ethane T=80°C; 0.0833333 h; Microwave irradiation; 2: With sodium hydroxide in water; 1,2-dichloro-ethane
参考文献
Park, Sang Hyun; Kwon, Hue Jeong; Jang, Seung Ho
Patent: US2007/36715 A1, 2007 ;
Location in patent: Page/Page column 4-5 ;
反应条件
hydrogenchloride in N-methyl-acetamide
参考文献
Pfizer Inc.
Patent: US4376204 A1, 1983 ;
Title/Abstract Full Text Show Details
Pfizer Inc.
Patent: US4483982 A1, 1984 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide Substitution; 18 h;
参考文献
Pike, Victor W.; McCarron, Julie A.; Hume, Susan P.; Ashworth, Sharon; Opacka-Juffry, Jolanta; et al.
Medicinal Chemistry Research, 1995 , vol. 5, # 2/3 p. 208 - 227
反应条件
1: K2CO3 / dimethylformamide 2: LAH / tetrahydrofuran 3: Et3N / CH2Cl2 View Scheme
参考文献
Zhuang; Kung
Journal of Medicinal Chemistry, 1994 , vol. 37, # 10 p. 1406 - 1407
反应条件
1: K2CO3 / dimethylformamide 2: LAH / tetrahydrofuran 3: Et3N / CH2Cl2 View Scheme
参考文献
Zhuang; Kung
Journal of Medicinal Chemistry, 1994 , vol. 37, # 10 p. 1406 - 1407
反应条件
1: 91 percent / potassium carbonate, / dimethylformamide / 18 h 2: 89 percent / BH3-Me2S / tetrahydrofuran / 2.5 h / Heating 3: 60 percent / triethylamine / CH2Cl2 / 20 °C View Scheme
参考文献
Mangin, Floriane; Dilly, Sebastien; Joly, Benoit; Scuvee-Moreau, Jacqueline; Evans, Jon; Setola, Vincent; Roth, Bryan L.; Liegeois, Jean-Francois
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4550 - 4554
反应条件
1: CH2Cl2 / 0.08 h / microwave irradiation 2: LiAlH4 / tetrahydrofuran / 0.08 h / microwave irradiation View Scheme
参考文献
Chemistry Letters, , vol. 35, # 11 p. 1304 - 1305
反应条件
1: 65 percent / acetone / 12 h / Heating
2: 52 percent / acetic acid / ethanol / Heating
View Scheme
参考文献
Singh, Tripti; Sharma, Shalabh; Srivastava; Kumar, Ashok
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 6 p. 1557 - 1563
