3-氨基-6-氯-4-苯基喹啉-2(1h)-酮合成路线 （共 7 条）
参考文献
Asis, Silvia E.; Bruno, Ana M.; Dominici, Diego A.; Bollini, Mariela; Gaozza, Carlos H.
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 1 p. 107 - 112
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; ammonia in ethanol
T=70°C; Further byproducts given;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4777 - 4793
反应条件
sulfuric acid; water
T=140 - 150°C; 0.5 h;
参考文献
Bahr; Usbeck
Pharmazie, 1981 , vol. 36, # 10 p. 668 - 671
反应条件
1: 77 percent / 1) Na/ethanol; 2) glacial acetic acid / ethanol / 2 h / Heating
2: 63 percent / conc. H2SO4/H2O / 0.5 h / 140 - 150 °C
View Scheme
参考文献
Bahr; Usbeck
Pharmazie, 1981 , vol. 36, # 10 p. 668 - 671
反应条件
aniline
2 h; Heating;
参考文献
Esteve, Marta E.; Gaozza, Carlos H.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1061 - 1063
反应条件
1: 90 percent / 0.25 h / Heating
2: 87 percent / aniline / 2 h / Heating
View Scheme
参考文献
Esteve, Marta E.; Gaozza, Carlos H.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1061 - 1063
反应条件
sodium hydroxide in acetone
T=0 - 5°C;
参考文献
Asis, Silvia E.; Bruno, Ana M.; Dominici, Diego A.; Bollini, Mariela; Gaozza, Carlos H.
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 1 p. 107 - 112
