十二氢-4H,8H,12H-4a,8a,12alpha-三氮杂苯并菲合成路线 (共 35 条)
反应条件
1: With N-chloro-succinimide in diethyl ether T=4 - 20°C; 2: With sodium methylate in methanol; diethyl ether 0.75 h; Heating;
参考文献
Gravel, Edmond; Poupon, Erwan; Hocquemiller, Reynald
Tetrahedron, 2006 , vol. 62, # 22 p. 5248 - 5253
反应条件
sodium methylate in methanol; diethyl ether 0.75 h; Reflux;
参考文献
Carney, Daniel W.; Truong, Jonathan V.; Sello, Jason K.
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 10279 - 10285
反应条件
in dichloromethane Yield given;
参考文献
Castro, C. E.; Jamin, Mary; Yokoyama, W.; Wade, Ruth
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4179 - 4187
反应条件
n-butyllithium; lithium perchlorate in tetrahydrofuran T=0°C; anodic oxidation; other amines, var. reagents; Product distribution;
参考文献
Fuchigami, Toshio; Sato, Takashi; Nonaka, Tsutomu
Journal of Organic Chemistry, 1986 , vol. 51, # 3 p. 366 - 369
反应条件
T=450°C; P=24 Torr; other temperatures and pressures; Product distributionMechanism;
参考文献
Viola, Alfred; Collins, John J.; Filipp, Nicholas; Locke, John S.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5067 - 5075
反应条件
in tetrahydrofuran T=30°C; Irradiation; Product distribution;
参考文献
Fuchigami, Toshio; Sato, Takashi; Nonaka, Tsutomu
Journal of Organic Chemistry, 1986 , vol. 51, # 3 p. 366 - 369
参考文献
Terao; Yasumoto; Ikeda; Sekiya
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 1 p. 105 - 108
反应条件
1: hydrogenchloride / water / 0.17 h / 20 °C / Inert atmosphere 2: N-bromosuccinmide; sodium hydroxide / water / 0.33 h / 45 °C / pH 1.9 / Inert atmosphere 3: hydrogenchloride / water / 3 h / 20 °C / pH 1.9 - 3 / Inert atmosphere View Scheme
参考文献
Rouchaud, Anne; Braekman, Jean-Claude
European Journal of Organic Chemistry, 2011 , # 12 p. 2346 - 2353
反应条件
in water 1 h; Ambient temperature; Yield given;
参考文献
Kimpe, Norbert De; Stevens, Christian
Journal of Organic Chemistry, 1993 , vol. 58, # 10 p. 2904 - 2906
反应条件
hydrogenchloride; diethyl ether Behandeln des Reaktionsprodukts mit HCN;
参考文献
Boehme et al.
Chemische Berichte, 1959 , vol. 92, p. 1608,1612