2-(4-(溴甲基)苯基)吡啶合成路线 （共 6 条）
反应条件
1: acetonitrile / 3 h / Ambient temperature
2: aq. HCl / 48 h / Heating
View Scheme
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
参考文献
Aoki, Shin; Matsuo, Yasuki; Ogura, Shiori; Ohwada, Hiroki; Hisamatsu, Yosuke; Moromizato, Shinsuke; Shiro, Motoo; Kitamura, Masanori
Inorganic Chemistry, 2011 , vol. 50, # 3 p. 806 - 818
反应条件
phosphorus tribromide in dichloromethane
T=20°C;
参考文献
Zeng, Xianshun; Batsanov, Andrei S.; Bryce, Martin R.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9589 - 9594
反应条件
1: 44 percent / aq. Na2CO3 / tetrakis(triphenylphosphine)palladium / tetrahydrofuran; toluene / 48 h / 80 °C
2: 99 percent / sodium borohydride / ethanol / 0.5 h / 20 °C
3: 83 percent / phosphorus tribromide / CH2Cl2 / 20 °C
View Scheme
参考文献
Zeng, Xianshun; Batsanov, Andrei S.; Bryce, Martin R.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9589 - 9594
反应条件
1: 44 percent / aq. Na2CO3 / tetrakis(triphenylphosphine)palladium / tetrahydrofuran; toluene / 48 h / 80 °C
2: 99 percent / sodium borohydride / ethanol / 0.5 h / 20 °C
3: 83 percent / phosphorus tribromide / CH2Cl2 / 20 °C
View Scheme
参考文献
Zeng, Xianshun; Batsanov, Andrei S.; Bryce, Martin R.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9589 - 9594
反应条件
1: 99 percent / sodium borohydride / ethanol / 0.5 h / 20 °C
2: 83 percent / phosphorus tribromide / CH2Cl2 / 20 °C
View Scheme
参考文献
Zeng, Xianshun; Batsanov, Andrei S.; Bryce, Martin R.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9589 - 9594
