甲基(2E)-二氢-2(3H)-呋喃亚基乙酸酯合成路线 （共 16 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 48 h;
参考文献
Bellur, Esen; Freifeld, Ilia; Boettcher, Dominique; Bornscheuer, Uwe T.; Langer, Peter
Tetrahedron, 2006 , vol. 62, # 29 p. 7132 - 7139
反应条件
N-bromosuccinmide in tetrachloromethane
3 h; Heating;
参考文献
Bellur, Esen; Langer, Peter
European Journal of Organic Chemistry, 2005 , # 22 p. 4815 - 4828
反应条件
N-bromosuccinmide in tetrachloromethane
3 h; Heating;
参考文献
Bellur, Esen; Langer, Peter
Synlett, 2004 , # 12 p. 2169 - 2171
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane
48 h; Heating;
参考文献
Bellur, Esen; Langer, Peter
Journal of Organic Chemistry, 2005 , vol. 70, # 24 p. 10013 - 10029
反应条件
1: acetoacetic acid methyl ester With lithium diisopropyl amide in tetrahydrofuran
T=0°C; 2 h;
2: 1-bromo-2-chloro-ethane in tetrahydrofuran
T=-78 - 20°C; 40 h;
参考文献
Bellur, Esen; Langer, Peter
Journal of Organic Chemistry, 2005 , vol. 70, # 24 p. 10013 - 10029
反应条件
oxygen; potassium iodide; PdI2
T=70°C; Oxidation; Cyclization; Carbonylation; Cycloisomerization; P=76000 Torr; 12 h; Further byproducts given;
参考文献
Gabriele, Bartolo; Salerno, Giuseppe; De Pascali, Francesca; Costa, Mirco; Chiusoli, Gian Paolo
Journal of Organometallic Chemistry, 2000 , vol. 593-594, p. 409 - 415
反应条件
sodium hydride in methanol
0.5 h; Ambient temperature;
参考文献
Pflieger, D.; Muckensturm, B.
Tetrahedron, 1989 , vol. 45, # 7 p. 2031 - 2040
反应条件
1: acetoacetic acid methyl ester With lithium diisopropyl amide in tetrahydrofuran; hexane
T=0°C; 0.75 h;
2: 1-bromo-2-chloro-ethane in tetrahydrofuran; hexane
T=-78 - 68°C; 28 h; Further stages. Title compound not separated from byproducts.;
参考文献
Langer; Holtz; Karime; Saleh
Journal of Organic Chemistry, 2001 , vol. 66, # 18 p. 6057 - 6063
反应条件
disodium hydrogenphosphate; iodine; sodium sulfate
T=65°C; 90 h;
参考文献
Calvet, Sandrine; David, Olivier; Vanucci-Bacque, Corinne; Fargeau-Bellassoued, Marie-Claude; Lhommet, Gerard
Tetrahedron, 2003 , vol. 59, # 33 p. 6333 - 6339
反应条件
disodium hydrogenphosphate; iodine; sodium sulfate
T=65°C;
参考文献
Calvet, Sandrine; David, Olivier; Vanucci-Bacque, Corinne; Fargeau-Bellassoued, Marie-Claude; Lhommet, Gerard
Tetrahedron, 2003 , vol. 59, # 33 p. 6333 - 6339
