2,3,5,6-四氟-4-三氟甲基苯甲酸合成路线 （共 14 条）
反应条件
1: 3.14 g / KF / 16 h / 200 °C
2: 1.) SbF5, 2.) H2O / 1.) 130 deg C, 10 h
View Scheme
参考文献
Karpov, V. M.; Panteleev, I. V.; Platonov, V. E.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1932 - 1938
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, p. 2183 - 2191
反应条件
water; SbF5
1.) 130 deg C, 10 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Karpov, V. M.; Panteleev, I. V.; Platonov, V. E.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1932 - 1938
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, p. 2183 - 2191
反应条件
(i) nBuLi, (ii) /BRN= 1900390/, (iii) aq. HCl; Multistep reaction;
参考文献
Tamborski,C.; Soloski,E.J.
Journal of Organic Chemistry, 1966 , vol. 31, p. 746 - 749
反应条件
water; SbF5; silica gel
T=75°C; 4 h; also in the absence of SiO2; other temp. and time; multistep 1.) 75 deg C, 4 h; Product distribution;
参考文献
Karpov, V. M.; Panteleev, I. V.; Platonov, V. E.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1932 - 1938
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, p. 2183 - 2191
