1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide T=65°C; 2 h;

1: (i) B2H6, THF, (ii) aq. H2O2, NaOH 2: CrO3, aq. H2SO4 / acetone View Scheme

1: toluene; tetrahydrofuran / 5 h / 80 °C 2: Jones reagent / acetone View Scheme

tetrahydrofuran; ammonia; lithium

暂无反应条件数据

1.1: pyridinium bromide perbromide / ethanol; water / 5.25 h / 24 - 27 °C / |Inert atmosphere; |Large scale 2.1: lithium carbonate; lithium bromide / N,N-dimethyl-formamide / 3 h / 110 - 115 °C / |Inert atmosphere 3.1: ozone / methanol / 6 h / -40 - -30 °C / |Inert atmosphere; |Large scale 4.1: sodium hydroxide / ethanol; water / 8 - 9 °C / |Inert atmosphere 4.2: 1 h / 5 - 7 °C 4.3: 8.75 h / 1 - 9 °C View Scheme

sodium hydride; oxalic acid diethyl ester anschliessend mit K2CO3 und CH3I in Aceton und Behandeln des Reaktionsprodukts mit Natriumaethylat in Aethanol;

1: O2, KOtBu / 2-methyl-propan-2-ol 2: aq. NH2OH*HCl 3: KOH / ethane-1,2-diol / 180 - 190 °C View Scheme

sodium hydrogencarbonate in dimethyl sulfoxide; ethyl acetate; toluene

1: 3.0 g / pyridinium tribromide / ethanol; CH2Cl2 / 3 h / 40 °C 2: 2.04 g / LiBr; Li2CO3 / dimethylformamide / 2 h / Heating View Scheme