(S)-(+)-2-己醇合成路线 (共 56 条)
反应条件
1: 69 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / Ambient temperature 2: NH2NH2*H2O / ethanol / 0.25 h / Heating View Scheme
参考文献
Sasse, Astrid; Kiec-Kononowicz, Katarzyna; Stark, Holger; Motyl, Malgorzata; Reidemeister, Sibylle; Ganellin, C. Robin; Ligneau, Xavier; Schwartz, Jean-Charles; Schunack, Walter
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 593 - 600
反应条件
1: 69 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / Ambient temperature 2: NH2NH2*H2O / ethanol / 0.25 h / Heating View Scheme
参考文献
Sasse, Astrid; Kiec-Kononowicz, Katarzyna; Stark, Holger; Motyl, Malgorzata; Reidemeister, Sibylle; Ganellin, C. Robin; Ligneau, Xavier; Schwartz, Jean-Charles; Schunack, Walter
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 593 - 600
反应条件
dipotassium hydrogenphosphate; phosphoric acid; EC 1.1.1.2 ketoreductase in hexane T=25°C; pH=7.3; 72 h; Equilibrium constant;
参考文献
Tewari, Yadu B.; Schantz, Michele M.; Phinney, Karen W.; Rozzell, J. David
Journal of Chemical Thermodynamics, 2005 , vol. 37, # 1 p. 89 - 96
反应条件
triethylamine in dichloromethane
参考文献
CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH
Patent: US2007/225519 A1, 2007 ;
参考文献
CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH
Patent: US2007/225519 A1, 2007 ;
反应条件
tributylphosphine in N,N-dimethyl-formamide
T=70°C; 1.16667 h;
参考文献
McNulty, James; Capretta, Alfredo; Laritchev, Vladimir; Dyck, Jeff; Robertson, Al J.
Angewandte Chemie - International Edition, 2003 , vol. 42, # 34 p. 4051 - 4054