(S)-(+)-2-己醇合成路线 （共 56 条）
反应条件
water; potassium hydroxide in ethanol Reflux; optical yield given as percent ee;
参考文献
Kalinowska, Iwona M.; Szawkao, Joanna; Krawczyk, Krzysztof K.; Maurin, Jan K.; Czarnocki, Zbigniew
Synthesis, 2011 , # 11 p. 1809 - 1813
反应条件
(1R,2R)-(+)-1,2-diphenylethylenediamine in ethanol Title compound not separated from byproducts;
参考文献
Imai, Yoshitane; Sato, Tomohiro; Kuroda, Reiko
Chemical Communications, 2005 , # 26 p. 3289 - 3291
反应条件
toluene-4-sulfonic acid in 1,4-dioxane; tert-butyl methyl ether; water T=40°C; 2 h;
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
D-glucopyranose; P450 BM3; perfluoroundecanoic acid in ethanol; N,N-dimethyl-formamide T=20°C; pH=8; 1 h; Enzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Zilly, Felipe E.; Acevedo, Juan P.; Augustyniak, Wojciech; Deege, Alfred; Reetz, Manfred T.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 12 p. 2720 - 2724
反应条件
1: 1-methyl-1-pentanol With Burkholderia cepacia lipase in isopropyl alcohol T=30°C; 0.5 h; Enzymatic reaction; 2: vinyl acetate in isopropyl alcohol T=30°C; 0.2 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Ema, Tadashi; Ura, Norichika; Yoshii, Masataka; Korenaga, Toshinobu; Sakai, Takashi
Tetrahedron, 2009 , vol. 65, # 46 p. 9583 - 9591
参考文献
Schober, Markus; Knaus, Tanja; Toesch, Michael; MacHeroux, Peter; Wagner, Ulrike; Faber, Kurt
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1737 - 1742
反应条件
1: 80 percent / baker's yeast, sucrose / H2O / 72 h / 37 °C 2: pyridine / 2 h / Ambient temperature 3: 72 percent / Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 4: 80 percent / aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Di Nunno, Leonardo; Franchini, Carlo; Nacci, Angelo; Scilimati, Antonio; Sinicropi, Maria Stefania
Tetrahedron Asymmetry, 1999 , vol. 10, # 10 p. 1913 - 1926
反应条件
1: pyridine / 2 h / Ambient temperature 2: 72 percent / Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 3: 80 percent / aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Di Nunno, Leonardo; Franchini, Carlo; Nacci, Angelo; Scilimati, Antonio; Sinicropi, Maria Stefania
Tetrahedron Asymmetry, 1999 , vol. 10, # 10 p. 1913 - 1926
反应条件
1: 72 percent / Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 2: 80 percent / aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Di Nunno, Leonardo; Franchini, Carlo; Nacci, Angelo; Scilimati, Antonio; Sinicropi, Maria Stefania
Tetrahedron Asymmetry, 1999 , vol. 10, # 10 p. 1913 - 1926
反应条件
1: 42 percent / p-TsOH, Na2SO4 / diethyl ether / Ambient temperature 2: 91 percent / Na2CO3, Raney-nickel / ethanol / Heating 3: 89 percent / p-TsOH, CH3OH / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Noe, Christian R.; Knollmueller, M.; Dungler, K.; Miculka, C.; Gaertner, P.
Monatshefte fuer Chemie, 1991 , vol. 122, # 8 p. 705 - 718
