N-叔丁氧羰基-L-苯丙氨酸甲酯合成路线 （共 114 条）
反应条件
triethylamine in dichloromethane 24 h; Ambient temperature;
参考文献
Sturrock, Edward; Nchinda, Aloysius; Chibale, Kelly
Patent: US2009/281160 A1, 2009 ;
Location in patent: Page/Page column 9 ;
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide 120 h;
参考文献
Boger, Joshua; Payne, Linda S.; Perlow, Debra S.; Lohr, Nancy S.; Poe, Martin; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1779 - 1790
反应条件
N-ethyl-N,N-diisopropylamine
参考文献
Kobayashi, Kazuya; Narumi, Tetsuo; Oishi, Shinya; Ohno, Hiroaki; Fujii, Nobutaka
Journal of Organic Chemistry, 2009 , vol. 74, # 12 p. 4626 - 4629
反应条件
4-methyl-morpholine; hydrogenchloride; sodium hydroxide in methanol; diethyl ether; water
参考文献
Tokuyama Corporation
Patent: US6458948 B1, 2002 ;
反应条件
sodium chloride; sodium carbonate in methanol; water; ethyl acetate
参考文献
Onishi, Tomoyuki; Otake, Yasuyuki; Nakazawa, Masakazu; Izawa, Kunisuke
Patent: US2002/35296 A1, 2002 ;
反应条件
cesium fluoride in N,N-dimethyl-formamide T=50°C; 6 h;
参考文献
Boger, Dale L.; Chen, Jyun-Hung; Saionz, Kurt W.
Journal of the American Chemical Society, 1996 , vol. 118, # 7 p. 1629 - 1644
反应条件
sodium tetrahydroborate; nickel dichloride in methanol T=0°C; 0.166667 h;
参考文献
Crich, David; Banerjee, Abhisek
Journal of the American Chemical Society, 2007 , vol. 129, # 33 p. 10064 - 10065
反应条件
phenyl 4,6-O-(R)-benzylidene-2,3-O-bis(diphenylphosphino)-.beta.-D-glucopyranoside; Rh(cyclo-octa-1,5-diene)2; hydrogen; tetrafluoroboric acid in methanol T=25°C; P=750.06 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Evans, David A.; Michael, Forrest E.; Tedrow, Jason S.; Campos, Kevin R.
Journal of the American Chemical Society, 2003 , vol. 125, # 12 p. 3534 - 3543
反应条件
anhydrous magnesium perchlorate in acetonitrile 16 h; Ambient temperature;
参考文献
Stafford, Jeffrey A.; Brackeen, Marcus F.; Karanewsky, Donald S.; Valvano, Nicole L.
Tetrahedron Letters, 1993 , vol. 34, # 49 p. 7873 - 7876
反应条件
(R)-methyl-BoPhoz; hydrogen; bis(cycloocta-1,5-diene)rhodium(I) trifluoromethanesulfonate in tetrahydrofuran T=25°C; P=517.148 Torr; 1 h;
参考文献
Boaz, Neil W.; Debenham, Sheryl D.; Mackenzie, Elaine B.; Large, Shannon E.
Organic Letters, 2002 , vol. 4, # 14 p. 2421 - 2424
