1,3-二氢-6-甲基-呋喃并[3,4-c]吡啶-7-醇合成路线 （共 16 条）
反应条件
1: 68 percent / Et3N, diphenoxyphosphorylazid / 24 h / Heating 2: 81 percent / 37percent HCl / ethanol; H2O / 2 h / Heating 3: 72 percent / NaNO2 / aq. HCl; H2O / 1 h / 90 - 95 °C View Scheme
参考文献
Geiger; Lalonde; Stoller; Schleich
Helvetica Chimica Acta, 1984 , vol. 67, # 5 p. 1274 - 1282
反应条件
1: 65 percent / KOH / ethanol; H2O / 5 h / Ambient temperature 2: 68 percent / Et3N, diphenoxyphosphorylazid / 24 h / Heating 3: 81 percent / 37percent HCl / ethanol; H2O / 2 h / Heating 4: 72 percent / NaNO2 / aq. HCl; H2O / 1 h / 90 - 95 °C View Scheme
参考文献
Geiger; Lalonde; Stoller; Schleich
Helvetica Chimica Acta, 1984 , vol. 67, # 5 p. 1274 - 1282
反应条件
1: 81 percent / 37percent HCl / ethanol; H2O / 2 h / Heating 2: 72 percent / NaNO2 / aq. HCl; H2O / 1 h / 90 - 95 °C View Scheme
参考文献
Geiger; Lalonde; Stoller; Schleich
Helvetica Chimica Acta, 1984 , vol. 67, # 5 p. 1274 - 1282
反应条件
1: CsF / ethanol / 87 h / Ambient temperature 2: 65 percent / KOH / ethanol; H2O / 5 h / Ambient temperature 3: 68 percent / Et3N, diphenoxyphosphorylazid / 24 h / Heating 4: 81 percent / 37percent HCl / ethanol; H2O / 2 h / Heating 5: 72 percent / NaNO2 / aq. HCl; H2O / 1 h / 90 - 95 °C View Scheme
参考文献
Geiger; Lalonde; Stoller; Schleich
Helvetica Chimica Acta, 1984 , vol. 67, # 5 p. 1274 - 1282
反应条件
palladium on activated charcoal; ethanol Hydrogenation;
参考文献
Naito; Ueno
Yakugaku Zasshi, 1959 , vol. 79, p. 1277,1280
Chem.Abstr., 1960 , p. 4566
反应条件
hydrogenchloride; acetic anhydride 1.) Et3N, reflux, 2 h; 2.) water, reflux, 75 min; Yield given. Multistep reaction;
参考文献
Geiger; Lalonde; Stoller; Schleich
Helvetica Chimica Acta, 1984 , vol. 67, # 5 p. 1274 - 1282
