1: With sodium methylate in methanol T=0°C; Inert atmosphereReflux; 2: With hydrogenchloride; water in methanol T=0 - 10°C;

1: carboxamidine hydrochloride With sodium ethanolate in ethanol 0.333333 h; 2: methyl 2-methoxypropanedioate in ethanol 16 h; 3: With acetic acid in ethanol pH=4 - 5;

triethylamine; trichlorophosphate in toluene T=100 - 105°C; 1.5 h; Reflux;