5-氨基-2,4-二氯嘧啶合成路线 （共 7 条）
反应条件
1: With iron; acetic acid 14 h; 2: With sodium carbonate in water; ethyl acetate
参考文献
Burger, Matthew; Lindvall, Mika
Patent: US2011/195980 A1, 2011 ;
Location in patent: Page/Page column 17 ;
反应条件
in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; N,N-dimethyl-aniline; trichlorophosphate
参考文献
Neurocrine Biosciences, Inc.
Patent: US5795905 A1, 1998 ;
反应条件
palladium on activated charcoal Hydrogenation;
参考文献
Whittaker
Journal of the Chemical Society, 1951 , p. 1565,1568
Journal of the Chemical Society, 1953 , p. 1646
Full Text Show Details
Smith; Christensen
Journal of Organic Chemistry, 1955 , vol. 20, p. 829,833,835
参考文献
Urban; Schnider
Helvetica Chimica Acta, 1958 , vol. 41, p. 1806,1812
反应条件
methanol
T=20°C; 1.5 h;
参考文献
CANCER RESEARCH TECHNOLOGY LIMITED; Bavetsias, Vassilios; Atrash, Butrus; Naud, Sébastien Gaston André; Sheldrake, Peter William; Blagg, Julian
Patent: US2013/345181 A1, 2013 ;
Location in patent: Paragraph 0785 ;
参考文献
CANCER RESEARCH TECHNOLOGY LIMITED; BAVETSIAS, Vassilios; ATRASH, Butrus; NAUD, Sebastien Gaston Andre; SHELDRAKE, Peter William; BLAGG, Julian
Patent: WO2012/123745 A1, 2012 ;
Location in patent: Page/Page column 117 ;
WO 2012/123745 A1
反应条件
sodium methylate; sodium in methanol; water
参考文献
Zeneca Limited
Patent: US5861401 A1, 1999 ;
