α-乙酰基-γ-丁内酯合成路线 （共 116 条）
参考文献
Zimmer et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 1667,1668, 1673
参考文献
American Cyanamid Company
Patent: US5364968 A1, 1994 ;
反应条件
sulfuric acid; magnesium in tetrachloromethane; ethanol; toluene
参考文献
Sumitomo Chemical Company, Limited
Patent: US4075346 A1, 1978 ;
反应条件
1: 88 percent / BF3*MeOH / ethanol / 72 h / Ambient temperature
2: 89 percent / Et3N / H2O / 18 h / Ambient temperature
3: 78 percent / POCl3 / 3 h / Heating
4: 70 percent / Na2CO3 / ethanol / 2 h / Heating
View Scheme
参考文献
Sato, Yasunobu; Shimoji, Yasuo; Fujita, Hiroshi; Nishino, Hiroshi; Mizuno, Hiroshi; et al.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 927 - 937
反应条件
1: 88 percent / BF3*MeOH / ethanol / 72 h / Ambient temperature
2: 89 percent / Et3N / H2O / 18 h / Ambient temperature
3: 78 percent / POCl3 / 3 h / Heating
View Scheme
参考文献
Sato, Yasunobu; Shimoji, Yasuo; Fujita, Hiroshi; Nishino, Hiroshi; Mizuno, Hiroshi; et al.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 927 - 937
反应条件
hydrogenchloride
T=90°C; 16 h;
参考文献
Hawksley, Daniel; Griffin, David A.; Leeper, Finian J.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 2 p. 144 - 148
