乙二醛-1,1-二甲基乙缩醛合成路线 （共 23 条）
反应条件
in methanol; water
T=20°C; 3 h;
参考文献
Kim, Dae-Kee; Jang, Yoojeung; Ho, Soon Lee; Park, Hyun-Ju; Yoo, Jakyung
Journal of Medicinal Chemistry, 2007 , vol. 50, # 13 p. 3143 - 3147
反应条件
potassium carbonate in cyclohexane
T=60°C; Horner-Wadsworth-Emmons reaction; 1 h;
参考文献
Satoh, Tsuyoshi; Hanaki, Noriko; Kuramochi, Yuko; Inoue, Yujiro; Hosoya, Kayo; Sakai, Ken
Tetrahedron, 2002 , vol. 58, # 13 p. 2533 - 2549
反应条件
1: With ammonium acetate in methanol; water
T=20°C; 16 h;
2: With hydrogenchloride in methanol; water
T=80°C; 0.5 h;
3: With sodium hydroxide in water
pH=9;
参考文献
H. LUNDBECK A/S; KEHLER, Jan; RITZEN, Andreas; LANGGAaRD, Morten; NIELSEN, Jacob; FARAH, Mohamed; LETH-PETERSEN, Sebastian; KILBURN, John Paul
Patent: WO2012/7006 A1, 2012 ;
Location in patent: Page/Page column 60 ;
WO 2012/007006 A1
